PRAD : Prostate adenocarcinoma

PRAD : Prostate adenocarcinoma

PRAD : Prostate adenocarcinoma

PRAD : Prostate adenocarcinoma

PRAD : Prostate adenocarcinoma

PRAD molecular subtypes: Cancer Genome Atlas Research Network, The Molecular Taxonomy of Primary Prostate Cancer. Cell. 2015;163(4):1011-25

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Hide statistics Comparison Statistical significance Normal-vs-ERG fusion 2.29230000003966E-06 Normal-vs-ETV1 fusion 3.7417999809719E-09 Normal-vs-ETV4 fusion 1.37010000011983E-07 Normal-vs-FLI1 fusion 3.798000E-01 Normal-vs-FOXA1 mutation 5.08939557164467E-11 Normal-vs-IDH1 mutation 6.779900E-04 Normal-vs-SPOP mutation 1.62447832963153E-12 ERG fusion-vs-ETV1 fusion 1.341940E-03 ERG fusion-vs-ETV4 fusion 9.366100E-04 ERG fusion-vs-FLI1 fusion 5.231200E-01 ERG fusion-vs-FOXA1 mutation 9.74330000014234E-07 ERG fusion-vs-IDH1 mutation 2.713900E-02 ERG fusion-vs-SPOP mutation 1.95680138759258E-11 ETV1 fusion-vs-ETV4 fusion 3.578000E-01 ETV1 fusion-vs-FLI1 fusion 2.224200E-02 ETV1 fusion-vs-FOXA1 mutation 4.862000E-02 ETV1 fusion-vs-IDH1 mutation 2.005400E-01 ETV1 fusion-vs-SPOP mutation 2.795800E-02 ETV4 fusion-vs-FLI1 fusion 3.250500E-02 ETV4 fusion-vs-FOXA1 mutation 3.474200E-01 ETV4 fusion-vs-IDH1 mutation 5.826600E-01 ETV4 fusion-vs-SPOP mutation 5.408200E-01 FLI1 fusion-vs-FOXA1 mutation 1.168570E-04 FLI1 fusion-vs-IDH1 mutation 1.288040E-02 FLI1 fusion-vs-SPOP mutation 2.789900E-04 FOXA1 mutation-vs-IDH1 mutation 8.617000E-01 FOXA1 mutation-vs-SPOP mutation 5.554000E-01 IDH1 mutation-vs-SPOP mutation 6.325200E-01

PRAD : Prostate adenocarcinoma

PRAD : Prostate adenocarcinoma

TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data