TOPBP1 expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 1.041350E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Stage1
2.937200E-01
Normal-vs-Stage2
1.171990E-01
Normal-vs-Stage3
2.311600E-01
Normal-vs-Stage4
7.967200E-01
Stage1-vs-Stage2
8.710600E-01
Stage1-vs-Stage3
7.649700E-02
Stage1-vs-Stage4
3.748600E-01
Stage2-vs-Stage3
4.761900E-02
Stage2-vs-Stage4
2.476400E-01
Stage3-vs-Stage4
7.627600E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Caucasian
1.080420E-01
Normal-vs-AfricanAmerican
3.607600E-01
Normal-vs-Asian
1.106560E-01
Caucasian-vs-AfricanAmerican
9.065800E-01
Caucasian-vs-Asian
3.523600E-01
AfricanAmerican-vs-Asian
4.778800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Male
1.019240E-01
Normal-vs-Female
1.355760E-01
Male-vs-Female
5.283600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
2.628400E-01
Normal-vs-Age(41-60Yrs)
2.710600E-01
Normal-vs-Age(61-80Yrs)
6.900300E-02
Normal-vs-Age(81-100Yrs)
2.395600E-01
Age(21-40Yrs)-vs-Age(41-60Yrs)
1.934570E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
5.319800E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
4.308600E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
1.455950E-02
Age(41-60Yrs)-vs-Age(81-100Yrs)
4.046200E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
6.492800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Non Drinker
7.277600E-02
Normal-vs-Daily Drinker
5.406000E-02
Normal-vs-Weekly Drinker
2.495800E-01
Normal-vs-Occasional Drinker
4.172000E-01
Normal-vs-Social Drinker
4.565400E-01
Non Drinker-vs-Daily Drinker
5.932800E-01
Non Drinker-vs-Weekly Drinker
4.605800E-01
Non Drinker-vs-Occasional Drinker
1.542620E-01
Non Drinker-vs-Social Drinker
5.830300E-02
Daily Drinker-vs-Weekly Drinker
2.658600E-01
Daily Drinker-vs-Occasional Drinker
8.678400E-02
Daily Drinker-vs-Social Drinker
2.787900E-02
Weekly Drinker-vs-Occasional Drinker
5.922400E-01
Weekly Drinker-vs-Social Drinker
3.615400E-01
Occasional Drinker-vs-Social Drinker
7.466400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Grade 1
9.558600E-01
Normal-vs-Grade 2
8.039600E-01
Normal-vs-Grade 3
6.999400E-01
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
1.990050E-02
Grade 1-vs-Grade 3
1.700930E-03
Grade 1-vs-Grade 4
9.558600E-01
Grade 2-vs-Grade 3
4.122200E-02
Grade 2-vs-Grade 4
8.039600E-01
Grade 3-vs-Grade 4
6.999400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Diabetic
7.412300E-02
Normal-vs-NonDiabetic
4.489800E-01
Diabetic-vs-NonDiabetic
5.841400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Pancreatitis
4.796800E-01
Normal-vs-NoPancreatitis
7.475900E-02
Pancreatitis-vs-NoPancreatitis
7.643600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-N0
1.387170E-01
Normal-vs-N1
4.866000E-01
N0-vs-N1
7.426800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-TP53-Mutant
7.026800E-01
Normal-vs-TP53-NonMutant
1.996620E-01
TP53-Mutant-vs-TP53-NonMutant
4.162400E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
