TOP2A expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 2.564200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
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Comparison Statistical significance
Normal-vs-Stage1
6.239400E-01
Normal-vs-Stage2
2.215200E-01
Normal-vs-Stage3
6.154800E-01
Normal-vs-Stage4
3.569600E-01
Stage1-vs-Stage2
3.141600E-01
Stage1-vs-Stage3
9.350800E-01
Stage1-vs-Stage4
5.153800E-01
Stage2-vs-Stage3
3.596800E-01
Stage2-vs-Stage4
9.826000E-01
Stage3-vs-Stage4
4.886400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
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Comparison Statistical significance
Normal-vs-Caucasian
2.592400E-01
Normal-vs-AfricanAmerican
3.494400E-01
Normal-vs-Asian
2.865600E-01
Caucasian-vs-AfricanAmerican
9.099200E-01
Caucasian-vs-Asian
1.123390E-01
AfricanAmerican-vs-Asian
5.017800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Male
3.050000E-01
Normal-vs-Female
2.029800E-01
Male-vs-Female
7.102200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
9.411400E-01
Normal-vs-Age(41-60Yrs)
1.904240E-01
Normal-vs-Age(61-80Yrs)
2.951600E-01
Normal-vs-Age(81-100Yrs)
2.832400E-01
Age(21-40Yrs)-vs-Age(41-60Yrs)
2.173600E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
3.363000E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
3.285400E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
1.065200E-01
Age(41-60Yrs)-vs-Age(81-100Yrs)
6.345800E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
7.198000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
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Comparison Statistical significance
Normal-vs-Non Drinker
3.272000E-01
Normal-vs-Daily Drinker
4.327200E-01
Normal-vs-Weekly Drinker
3.114800E-01
Normal-vs-Occasional Drinker
2.270200E-01
Normal-vs-Social Drinker
2.608600E-01
Non Drinker-vs-Daily Drinker
5.331600E-01
Non Drinker-vs-Weekly Drinker
8.951600E-01
Non Drinker-vs-Occasional Drinker
2.231800E-01
Non Drinker-vs-Social Drinker
4.048000E-01
Daily Drinker-vs-Weekly Drinker
5.083800E-01
Daily Drinker-vs-Occasional Drinker
1.037980E-01
Daily Drinker-vs-Social Drinker
1.978760E-01
Weekly Drinker-vs-Occasional Drinker
3.843600E-01
Weekly Drinker-vs-Social Drinker
5.611600E-01
Occasional Drinker-vs-Social Drinker
7.732600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
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Comparison Statistical significance
Normal-vs-Grade 1
6.791000E-01
Normal-vs-Grade 2
8.238800E-01
Normal-vs-Grade 3
8.762200E-01
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
1.069790E-02
Grade 1-vs-Grade 3
1.739910E-03
Grade 1-vs-Grade 4
6.791000E-01
Grade 2-vs-Grade 3
3.466000E-01
Grade 2-vs-Grade 4
8.238800E-01
Grade 3-vs-Grade 4
8.762200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
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Comparison Statistical significance
Normal-vs-Diabetic
4.942000E-01
Normal-vs-NonDiabetic
2.197200E-01
Diabetic-vs-NonDiabetic
1.026190E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
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Comparison Statistical significance
Normal-vs-Pancreatitis
1.298950E-01
Normal-vs-NoPancreatitis
2.954000E-01
Pancreatitis-vs-NoPancreatitis
6.294200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison Statistical significance
Normal-vs-N0
2.667400E-01
Normal-vs-N1
2.361400E-01
N0-vs-N1
5.754800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison Statistical significance
Normal-vs-TP53-Mutant
4.900000E-02
Normal-vs-TP53-NonMutant
3.638400E-01
TP53-Mutant-vs-TP53-NonMutant
1.04680000001522E-06
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
