SIRT1 expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 9.579900E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
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Comparison Statistical significance
Normal-vs-Stage1
2.368200E-01
Normal-vs-Stage2
1.078600E-01
Normal-vs-Stage3
2.499700E-02
Normal-vs-Stage4
6.611400E-01
Stage1-vs-Stage2
7.050400E-01
Stage1-vs-Stage3
1.610400E-01
Stage1-vs-Stage4
3.827200E-01
Stage2-vs-Stage3
1.743370E-01
Stage2-vs-Stage4
1.798410E-01
Stage3-vs-Stage4
4.019700E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
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Comparison Statistical significance
Normal-vs-Caucasian
8.366500E-02
Normal-vs-AfricanAmerican
7.656000E-01
Normal-vs-Asian
3.443600E-02
Caucasian-vs-AfricanAmerican
7.201600E-02
Caucasian-vs-Asian
2.335400E-01
AfricanAmerican-vs-Asian
5.252400E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Male
9.139900E-02
Normal-vs-Female
1.129350E-01
Male-vs-Female
3.679400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
1.039980E-01
Normal-vs-Age(41-60Yrs)
3.090600E-01
Normal-vs-Age(61-80Yrs)
5.733900E-02
Normal-vs-Age(81-100Yrs)
3.357500E-03
Age(21-40Yrs)-vs-Age(41-60Yrs)
6.386400E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
7.175400E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
1.997180E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
3.496600E-03
Age(41-60Yrs)-vs-Age(81-100Yrs)
1.444070E-02
Age(61-80Yrs)-vs-Age(81-100Yrs)
3.373200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
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Comparison Statistical significance
Normal-vs-Non Drinker
2.646300E-02
Normal-vs-Daily Drinker
4.099500E-02
Normal-vs-Weekly Drinker
2.849800E-02
Normal-vs-Occasional Drinker
8.689500E-02
Normal-vs-Social Drinker
1.995150E-01
Non Drinker-vs-Daily Drinker
8.326600E-01
Non Drinker-vs-Weekly Drinker
6.721000E-01
Non Drinker-vs-Occasional Drinker
3.214000E-01
Non Drinker-vs-Social Drinker
5.125000E-01
Daily Drinker-vs-Weekly Drinker
8.377000E-01
Daily Drinker-vs-Occasional Drinker
2.903000E-01
Daily Drinker-vs-Social Drinker
4.691200E-01
Weekly Drinker-vs-Occasional Drinker
2.303800E-01
Weekly Drinker-vs-Social Drinker
4.162600E-01
Occasional Drinker-vs-Social Drinker
8.942600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
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Comparison Statistical significance
Normal-vs-Grade 1
4.852100E-02
Normal-vs-Grade 2
1.008470E-02
Normal-vs-Grade 3
1.697840E-02
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
5.813800E-01
Grade 1-vs-Grade 3
9.783000E-01
Grade 1-vs-Grade 4
4.852100E-02
Grade 2-vs-Grade 3
4.740400E-01
Grade 2-vs-Grade 4
1.008470E-02
Grade 3-vs-Grade 4
1.697840E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
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Comparison Statistical significance
Normal-vs-Diabetic
3.751800E-02
Normal-vs-NonDiabetic
5.251600E-02
Diabetic-vs-NonDiabetic
8.997800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
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Comparison Statistical significance
Normal-vs-Pancreatitis
1.699700E-03
Normal-vs-NoPancreatitis
6.897800E-02
Pancreatitis-vs-NoPancreatitis
7.321900E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison Statistical significance
Normal-vs-N0
7.632500E-02
Normal-vs-N1
1.197990E-01
N0-vs-N1
4.709800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison Statistical significance
Normal-vs-TP53-Mutant
9.376400E-02
Normal-vs-TP53-NonMutant
3.455200E-01
TP53-Mutant-vs-TP53-NonMutant
7.306000E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
