POLE3 expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 7.043000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
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Comparison Statistical significance
Normal-vs-Stage1
3.950800E-01
Normal-vs-Stage2
7.677000E-01
Normal-vs-Stage3
2.640600E-01
Normal-vs-Stage4
6.576200E-01
Stage1-vs-Stage2
3.682800E-01
Stage1-vs-Stage3
5.958800E-01
Stage1-vs-Stage4
1.803190E-01
Stage2-vs-Stage3
1.833410E-01
Stage2-vs-Stage4
2.655600E-01
Stage3-vs-Stage4
1.475620E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
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Comparison Statistical significance
Normal-vs-Caucasian
6.988000E-01
Normal-vs-AfricanAmerican
6.581200E-01
Normal-vs-Asian
9.553200E-01
Caucasian-vs-AfricanAmerican
9.476800E-01
Caucasian-vs-Asian
5.574400E-01
AfricanAmerican-vs-Asian
6.863200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Male
5.950600E-01
Normal-vs-Female
8.455200E-01
Male-vs-Female
2.315400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
2.039000E-01
Normal-vs-Age(41-60Yrs)
8.161400E-01
Normal-vs-Age(61-80Yrs)
4.979200E-01
Normal-vs-Age(81-100Yrs)
7.075000E-01
Age(21-40Yrs)-vs-Age(41-60Yrs)
8.136100E-02
Age(21-40Yrs)-vs-Age(61-80Yrs)
3.637600E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
2.798000E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
1.496240E-03
Age(41-60Yrs)-vs-Age(81-100Yrs)
2.413800E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
6.135600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
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Comparison Statistical significance
Normal-vs-Non Drinker
5.771600E-01
Normal-vs-Daily Drinker
6.256600E-01
Normal-vs-Weekly Drinker
8.620000E-01
Normal-vs-Occasional Drinker
8.467600E-01
Normal-vs-Social Drinker
9.348600E-01
Non Drinker-vs-Daily Drinker
7.982200E-01
Non Drinker-vs-Weekly Drinker
5.119000E-01
Non Drinker-vs-Occasional Drinker
4.597600E-01
Non Drinker-vs-Social Drinker
2.987600E-01
Daily Drinker-vs-Weekly Drinker
6.496800E-01
Daily Drinker-vs-Occasional Drinker
6.091400E-01
Daily Drinker-vs-Social Drinker
3.956200E-01
Weekly Drinker-vs-Occasional Drinker
9.984800E-01
Weekly Drinker-vs-Social Drinker
8.065600E-01
Occasional Drinker-vs-Social Drinker
7.867400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
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Comparison Statistical significance
Normal-vs-Grade 1
8.017000E-01
Normal-vs-Grade 2
9.392000E-01
Normal-vs-Grade 3
9.272600E-01
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
7.390900E-04
Grade 1-vs-Grade 3
6.557500E-03
Grade 1-vs-Grade 4
8.017000E-01
Grade 2-vs-Grade 3
7.294400E-01
Grade 2-vs-Grade 4
9.392000E-01
Grade 3-vs-Grade 4
9.272600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
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Comparison Statistical significance
Normal-vs-Diabetic
6.056400E-01
Normal-vs-NonDiabetic
7.167000E-01
Diabetic-vs-NonDiabetic
5.290000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
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Comparison Statistical significance
Normal-vs-Pancreatitis
8.444800E-01
Normal-vs-NoPancreatitis
7.029800E-01
Pancreatitis-vs-NoPancreatitis
6.771000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison Statistical significance
Normal-vs-N0
5.356000E-01
Normal-vs-N1
8.064000E-01
N0-vs-N1
2.429000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison Statistical significance
Normal-vs-TP53-Mutant
6.494200E-01
Normal-vs-TP53-NonMutant
5.956000E-01
TP53-Mutant-vs-TP53-NonMutant
1.075520E-03
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
