POLE2 expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 1.62458935193399E-12
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Stage1
1.867190E-01
Normal-vs-Stage2
1.62447832963153E-12
Normal-vs-Stage3
1.438020E-01
Normal-vs-Stage4
9.736000E-02
Stage1-vs-Stage2
3.226600E-01
Stage1-vs-Stage3
6.732000E-01
Stage1-vs-Stage4
7.489400E-01
Stage2-vs-Stage3
7.250200E-01
Stage2-vs-Stage4
6.228000E-01
Stage3-vs-Stage4
8.899600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Caucasian
1.62447832963153E-12
Normal-vs-AfricanAmerican
8.112400E-02
Normal-vs-Asian
3.358300E-03
Caucasian-vs-AfricanAmerican
2.346600E-01
Caucasian-vs-Asian
4.670800E-01
AfricanAmerican-vs-Asian
3.802000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Male
8.27116153345742E-14
Normal-vs-Female
2.61479726759717E-11
Male-vs-Female
7.352200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
6.628400E-01
Normal-vs-Age(41-60Yrs)
1.14889999736079E-08
Normal-vs-Age(61-80Yrs)
2.04281036531029E-14
Normal-vs-Age(81-100Yrs)
1.316540E-03
Age(21-40Yrs)-vs-Age(41-60Yrs)
3.058000E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
2.524600E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
1.772970E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
4.948200E-01
Age(41-60Yrs)-vs-Age(81-100Yrs)
4.394200E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
7.037800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Non Drinker
6.10059999999191E-05
Normal-vs-Daily Drinker
3.810200E-04
Normal-vs-Weekly Drinker
1.131940E-02
Normal-vs-Occasional Drinker
5.68669999999605E-05
Normal-vs-Social Drinker
9.444200E-03
Non Drinker-vs-Daily Drinker
5.553200E-01
Non Drinker-vs-Weekly Drinker
4.678200E-01
Non Drinker-vs-Occasional Drinker
5.951600E-01
Non Drinker-vs-Social Drinker
6.030800E-01
Daily Drinker-vs-Weekly Drinker
8.257200E-01
Daily Drinker-vs-Occasional Drinker
9.243600E-01
Daily Drinker-vs-Social Drinker
3.481400E-01
Weekly Drinker-vs-Occasional Drinker
7.703000E-01
Weekly Drinker-vs-Social Drinker
3.373400E-01
Occasional Drinker-vs-Social Drinker
3.073400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Grade 1
6.360200E-01
Normal-vs-Grade 2
7.241200E-01
Normal-vs-Grade 3
7.655400E-01
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
1.026120E-02
Grade 1-vs-Grade 3
9.848700E-04
Grade 1-vs-Grade 4
6.360200E-01
Grade 2-vs-Grade 3
2.093000E-01
Grade 2-vs-Grade 4
7.241200E-01
Grade 3-vs-Grade 4
7.655400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Diabetic
1.86439999999566E-05
Normal-vs-NonDiabetic
1.0547118733939E-14
Diabetic-vs-NonDiabetic
4.479400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Pancreatitis
9.358000E-03
Normal-vs-NoPancreatitis
1.62736490949555E-12
Pancreatitis-vs-NoPancreatitis
6.482800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-N0
6.96830371182955E-11
Normal-vs-N1
1.01030295240889E-14
N0-vs-N1
5.928000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-TP53-Mutant
2.93659985217687E-10
Normal-vs-TP53-NonMutant
2.45179999999179E-05
TP53-Mutant-vs-TP53-NonMutant
9.71680000000363E-05
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
