MTHFD2 expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 4.815800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
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Comparison Statistical significance
Normal-vs-Stage1
6.147000E-01
Normal-vs-Stage2
4.171800E-01
Normal-vs-Stage3
7.618200E-01
Normal-vs-Stage4
1.447540E-02
Stage1-vs-Stage2
8.712000E-01
Stage1-vs-Stage3
4.871000E-01
Stage1-vs-Stage4
5.854600E-01
Stage2-vs-Stage3
2.730800E-01
Stage2-vs-Stage4
1.586650E-01
Stage3-vs-Stage4
1.226280E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
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Comparison Statistical significance
Normal-vs-Caucasian
4.442000E-01
Normal-vs-AfricanAmerican
3.435200E-01
Normal-vs-Asian
3.409400E-01
Caucasian-vs-AfricanAmerican
6.417800E-01
Caucasian-vs-Asian
4.407500E-04
AfricanAmerican-vs-Asian
2.138800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Male
4.755800E-01
Normal-vs-Female
4.925600E-01
Male-vs-Female
5.519400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
6.675600E-01
Normal-vs-Age(41-60Yrs)
3.219200E-01
Normal-vs-Age(61-80Yrs)
5.733400E-01
Normal-vs-Age(81-100Yrs)
4.872200E-01
Age(21-40Yrs)-vs-Age(41-60Yrs)
1.511200E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
2.596000E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
3.022800E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
3.639900E-02
Age(41-60Yrs)-vs-Age(81-100Yrs)
6.976600E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
4.784600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
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Comparison Statistical significance
Normal-vs-Non Drinker
5.990800E-01
Normal-vs-Daily Drinker
6.436600E-01
Normal-vs-Weekly Drinker
8.254000E-01
Normal-vs-Occasional Drinker
5.189400E-01
Normal-vs-Social Drinker
5.546800E-01
Non Drinker-vs-Daily Drinker
8.691200E-01
Non Drinker-vs-Weekly Drinker
5.614600E-01
Non Drinker-vs-Occasional Drinker
4.636400E-01
Non Drinker-vs-Social Drinker
9.281400E-01
Daily Drinker-vs-Weekly Drinker
6.682400E-01
Daily Drinker-vs-Occasional Drinker
4.109600E-01
Daily Drinker-vs-Social Drinker
8.175000E-01
Weekly Drinker-vs-Occasional Drinker
3.097400E-01
Weekly Drinker-vs-Social Drinker
5.441200E-01
Occasional Drinker-vs-Social Drinker
5.311800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
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Comparison Statistical significance
Normal-vs-Grade 1
8.755200E-01
Normal-vs-Grade 2
9.264600E-01
Normal-vs-Grade 3
9.022000E-01
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
1.801220E-01
Grade 1-vs-Grade 3
1.158620E-01
Grade 1-vs-Grade 4
8.755200E-01
Grade 2-vs-Grade 3
6.909800E-01
Grade 2-vs-Grade 4
9.264600E-01
Grade 3-vs-Grade 4
9.022000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
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Comparison Statistical significance
Normal-vs-Diabetic
4.203000E-01
Normal-vs-NonDiabetic
6.663600E-01
Diabetic-vs-NonDiabetic
4.682200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
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Comparison Statistical significance
Normal-vs-Pancreatitis
5.332200E-01
Normal-vs-NoPancreatitis
5.813200E-01
Pancreatitis-vs-NoPancreatitis
7.811000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison Statistical significance
Normal-vs-N0
5.731200E-01
Normal-vs-N1
4.011200E-01
N0-vs-N1
2.106200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison Statistical significance
Normal-vs-TP53-Mutant
4.078200E-01
Normal-vs-TP53-NonMutant
8.430000E-01
TP53-Mutant-vs-TP53-NonMutant
1.910000E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
