MKNK1 expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 4.639200E-04
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
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Comparison Statistical significance
Normal-vs-Stage1
7.117800E-03
Normal-vs-Stage2
5.559000E-04
Normal-vs-Stage3
7.659000E-03
Normal-vs-Stage4
8.602000E-03
Stage1-vs-Stage2
2.411800E-01
Stage1-vs-Stage3
9.640800E-01
Stage1-vs-Stage4
8.395600E-01
Stage2-vs-Stage3
3.091800E-01
Stage2-vs-Stage4
4.507200E-01
Stage3-vs-Stage4
7.422200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
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Comparison Statistical significance
Normal-vs-Caucasian
7.159000E-04
Normal-vs-AfricanAmerican
1.008280E-02
Normal-vs-Asian
2.041400E-03
Caucasian-vs-AfricanAmerican
5.279000E-01
Caucasian-vs-Asian
1.129850E-01
AfricanAmerican-vs-Asian
6.353600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Male
3.161300E-04
Normal-vs-Female
1.376750E-03
Male-vs-Female
5.842400E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
5.219600E-02
Normal-vs-Age(41-60Yrs)
2.34809999999364E-05
Normal-vs-Age(61-80Yrs)
1.537660E-03
Normal-vs-Age(81-100Yrs)
1.851680E-02
Age(21-40Yrs)-vs-Age(41-60Yrs)
8.251800E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
8.144400E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
7.275400E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
7.155600E-01
Age(41-60Yrs)-vs-Age(81-100Yrs)
6.392200E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
6.893800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
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Comparison Statistical significance
Normal-vs-Non Drinker
4.442000E-03
Normal-vs-Daily Drinker
2.938700E-03
Normal-vs-Weekly Drinker
3.720600E-03
Normal-vs-Occasional Drinker
1.312020E-02
Normal-vs-Social Drinker
4.440500E-03
Non Drinker-vs-Daily Drinker
8.648000E-01
Non Drinker-vs-Weekly Drinker
9.685800E-01
Non Drinker-vs-Occasional Drinker
9.750600E-01
Non Drinker-vs-Social Drinker
6.879600E-01
Daily Drinker-vs-Weekly Drinker
8.456400E-01
Daily Drinker-vs-Occasional Drinker
9.085400E-01
Daily Drinker-vs-Social Drinker
7.945800E-01
Weekly Drinker-vs-Occasional Drinker
9.509000E-01
Weekly Drinker-vs-Social Drinker
6.696800E-01
Occasional Drinker-vs-Social Drinker
7.477400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
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Comparison Statistical significance
Normal-vs-Grade 1
8.755800E-01
Normal-vs-Grade 2
6.129200E-01
Normal-vs-Grade 3
6.893400E-01
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
4.458600E-01
Grade 1-vs-Grade 3
5.894000E-01
Grade 1-vs-Grade 4
8.755800E-01
Grade 2-vs-Grade 3
7.458200E-01
Grade 2-vs-Grade 4
6.129200E-01
Grade 3-vs-Grade 4
6.893400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
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Comparison Statistical significance
Normal-vs-Diabetic
1.737650E-03
Normal-vs-NonDiabetic
1.799130E-04
Diabetic-vs-NonDiabetic
4.373200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
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Comparison Statistical significance
Normal-vs-Pancreatitis
2.757800E-03
Normal-vs-NoPancreatitis
3.046200E-04
Pancreatitis-vs-NoPancreatitis
9.202800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison Statistical significance
Normal-vs-N0
9.390700E-04
Normal-vs-N1
5.808600E-04
N0-vs-N1
5.337900E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison Statistical significance
Normal-vs-TP53-Mutant
2.47289999999456E-05
Normal-vs-TP53-NonMutant
5.222100E-03
TP53-Mutant-vs-TP53-NonMutant
9.944100E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
