MELK expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 2.119000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
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Comparison Statistical significance
Normal-vs-Stage1
3.932200E-01
Normal-vs-Stage2
1.883020E-01
Normal-vs-Stage3
4.614200E-01
Normal-vs-Stage4
3.649600E-01
Stage1-vs-Stage2
5.247000E-01
Stage1-vs-Stage3
6.018200E-01
Stage1-vs-Stage4
8.447600E-01
Stage2-vs-Stage3
2.875800E-01
Stage2-vs-Stage4
4.609200E-01
Stage3-vs-Stage4
6.940200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
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Comparison Statistical significance
Normal-vs-Caucasian
2.209200E-01
Normal-vs-AfricanAmerican
2.939600E-01
Normal-vs-Asian
1.487020E-01
Caucasian-vs-AfricanAmerican
5.260200E-01
Caucasian-vs-Asian
8.097000E-01
AfricanAmerican-vs-Asian
4.153800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Male
2.244400E-01
Normal-vs-Female
2.071800E-01
Male-vs-Female
6.997000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
9.811600E-01
Normal-vs-Age(41-60Yrs)
2.162000E-01
Normal-vs-Age(61-80Yrs)
2.160600E-01
Normal-vs-Age(81-100Yrs)
1.700420E-01
Age(21-40Yrs)-vs-Age(41-60Yrs)
2.247200E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
2.235000E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
1.922410E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
9.226400E-01
Age(41-60Yrs)-vs-Age(81-100Yrs)
9.745600E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
9.838400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
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Comparison Statistical significance
Normal-vs-Non Drinker
2.632600E-01
Normal-vs-Daily Drinker
2.373800E-01
Normal-vs-Weekly Drinker
2.697800E-02
Normal-vs-Occasional Drinker
1.920420E-01
Normal-vs-Social Drinker
1.581370E-01
Non Drinker-vs-Daily Drinker
8.118000E-01
Non Drinker-vs-Weekly Drinker
3.078200E-01
Non Drinker-vs-Occasional Drinker
2.409800E-01
Non Drinker-vs-Social Drinker
2.445000E-01
Daily Drinker-vs-Weekly Drinker
3.856600E-01
Daily Drinker-vs-Occasional Drinker
3.728600E-01
Daily Drinker-vs-Social Drinker
3.722200E-01
Weekly Drinker-vs-Occasional Drinker
8.321000E-01
Weekly Drinker-vs-Social Drinker
8.317400E-01
Occasional Drinker-vs-Social Drinker
9.956400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
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Comparison Statistical significance
Normal-vs-Grade 1
5.858400E-01
Normal-vs-Grade 2
6.715200E-01
Normal-vs-Grade 3
7.008800E-01
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
3.954300E-04
Grade 1-vs-Grade 3
3.433600E-04
Grade 1-vs-Grade 4
5.858400E-01
Grade 2-vs-Grade 3
3.464400E-01
Grade 2-vs-Grade 4
6.715200E-01
Grade 3-vs-Grade 4
7.008800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
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Comparison Statistical significance
Normal-vs-Diabetic
3.361400E-01
Normal-vs-NonDiabetic
1.910010E-01
Diabetic-vs-NonDiabetic
6.240400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
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Comparison Statistical significance
Normal-vs-Pancreatitis
4.405600E-02
Normal-vs-NoPancreatitis
2.459800E-01
Pancreatitis-vs-NoPancreatitis
7.789400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison Statistical significance
Normal-vs-N0
2.207600E-01
Normal-vs-N1
1.932240E-01
N0-vs-N1
6.779200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison Statistical significance
Normal-vs-TP53-Mutant
5.09199999942922E-08
Normal-vs-TP53-NonMutant
3.919700E-03
TP53-Mutant-vs-TP53-NonMutant
1.61300999999003E-05
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
