APPL2 expression based on
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Comparison Statistical significance Normal-vs-Primary 8.371200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 3 samples.
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Comparison Statistical significance
Normal-vs-Stage1
4.992200E-01
Normal-vs-Stage2
6.616400E-01
Normal-vs-Stage3
8.843700E-02
Normal-vs-Stage4
4.622000E-01
Stage1-vs-Stage2
7.137900E-02
Stage1-vs-Stage3
4.120300E-02
Stage1-vs-Stage4
9.341400E-01
Stage2-vs-Stage3
1.951170E-01
Stage2-vs-Stage4
1.644160E-01
Stage3-vs-Stage4
1.976020E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 5 samples.
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Comparison Statistical significance
Normal-vs-Caucasian
8.710800E-01
Normal-vs-AfricanAmerican
7.792800E-01
Normal-vs-Asian
1.902360E-01
Caucasian-vs-AfricanAmerican
8.972800E-01
Caucasian-vs-Asian
1.178640E-01
AfricanAmerican-vs-Asian
2.452000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Male
8.898200E-01
Normal-vs-Female
7.425800E-01
Male-vs-Female
6.728800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Age(21-40Yrs)
5.884200E-01
Normal-vs-Age(41-60Yrs)
9.699000E-01
Normal-vs-Age(61-80Yrs)
7.478600E-01
Normal-vs-Age(81-100Yrs)
7.830000E-01
Age(21-40Yrs)-vs-Age(41-60Yrs)
4.855000E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
3.725600E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
3.492200E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
1.488760E-01
Age(41-60Yrs)-vs-Age(81-100Yrs)
5.591000E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
8.312000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Drinking status is not available for 80 samples.
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Comparison Statistical significance
Normal-vs-Non Drinker
4.677600E-01
Normal-vs-Daily Drinker
4.523400E-01
Normal-vs-Weekly Drinker
2.989400E-01
Normal-vs-Occasional Drinker
9.381800E-01
Normal-vs-Social Drinker
7.395400E-01
Non Drinker-vs-Daily Drinker
8.584800E-01
Non Drinker-vs-Weekly Drinker
6.049800E-01
Non Drinker-vs-Occasional Drinker
2.655600E-01
Non Drinker-vs-Social Drinker
5.249800E-02
Daily Drinker-vs-Weekly Drinker
4.788400E-01
Daily Drinker-vs-Occasional Drinker
3.347400E-01
Daily Drinker-vs-Social Drinker
7.041700E-02
Weekly Drinker-vs-Occasional Drinker
1.906790E-01
Weekly Drinker-vs-Social Drinker
4.832000E-02
Occasional Drinker-vs-Social Drinker
4.743600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
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Comparison Statistical significance
Normal-vs-Grade 1
2.879800E-01
Normal-vs-Grade 2
4.991600E-02
Normal-vs-Grade 3
4.337700E-02
Normal-vs-Grade 4
1.000000E+00
Grade 1-vs-Grade 2
2.726600E-01
Grade 1-vs-Grade 3
4.310800E-01
Grade 1-vs-Grade 4
2.879800E-01
Grade 2-vs-Grade 3
4.488200E-01
Grade 2-vs-Grade 4
4.991600E-02
Grade 3-vs-Grade 4
4.337700E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Diabetes status information is not available for 30 samples.
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Comparison Statistical significance
Normal-vs-Diabetic
5.412200E-01
Normal-vs-NonDiabetic
8.314200E-01
Diabetic-vs-NonDiabetic
3.147400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Pancreatitis status is not available for 39 samples.
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Comparison Statistical significance
Normal-vs-Pancreatitis
1.213590E-01
Normal-vs-NoPancreatitis
8.237000E-01
Pancreatitis-vs-NoPancreatitis
3.103600E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 1 sample and cancer in nearby lymph nodes cannot be measured (NX) in 4 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison Statistical significance
Normal-vs-N0
9.434400E-01
Normal-vs-N1
6.982400E-01
N0-vs-N1
6.239000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PAAD : Pancreatic adenocarcinoma *
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 3 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison Statistical significance
Normal-vs-TP53-Mutant
7.930000E-01
Normal-vs-TP53-NonMutant
7.390400E-01
TP53-Mutant-vs-TP53-NonMutant
4.493900E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
