DNMT3A expression profile based on
LGG : Brain lower grade glioma Note
Patient race information is not available for 12 samples and 1 sample is from American Indian.
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Comparison Statistical significance
Caucasian-vs-AfricanAmerican
4.168200E-01
Caucasian-vs-Asian
8.859200E-01
AfricanAmerican-vs-Asian
9.158000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
LGG : Brain lower grade glioma Note
Patient gender information is not available for 2 samples.
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Comparison Statistical significance
Male-vs-Female
3.093600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
LGG : Brain lower grade glioma Note
Patient age information is not available for 2 samples.
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Comparison Statistical significance
Age(21-40Yrs)-vs-Age(41-60Yrs)
2.255800E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
5.977900E-02
Age(21-40Yrs)-vs-Age(81-100Yrs)
N/A
Age(41-60Yrs)-vs-Age(61-80Yrs)
4.657800E-01
Age(41-60Yrs)-vs-Age(81-100Yrs)
N/A
Age(61-80Yrs)-vs-Age(81-100Yrs)
N/A
Pan-cancer view
Methylation
Survival
Correlated genes
LGG : Brain lower grade glioma Note
Tumor grade information is not available for 3 samples.
Subtype descriptions Grade 1 Well differentiated (low grade)
Grade 2 Moderately differentiated (intermediate grade) Grade 3 Poorly differentiated (high grade)
Grade 4 Undifferentiated (high grade)
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Comparison Statistical significance
Grade 2-vs-Grade 3
1.93579596796667E-11
Pan-cancer view
Methylation
Survival
Correlated genes
LGG : Brain lower grade glioma Note
Histological subtype information is not available for 1 sample.
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Comparison Statistical significance
Astrocytoma-vs-Oligoastrocytoma
3.583500E-02
Astrocytoma-vs-Oligodendroglioma
2.17129999999788E-05
Oligoastrocytoma-vs-Oligodendroglioma
1.106030E-01
Pan-cancer view
Methylation
Survival
Correlated genes
LGG : Brain lower grade glioma Note
Whole exome sequencing data is not available for 4 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data.
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Comparison Statistical significance
TP53-Mutant-vs-TP53-NonMutant
9.131600E-01
Pan-cancer view
Methylation
Survival
Correlated genes
