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TOPBP1 expression based on
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KIRC : Kidney renal clear cell carcinoma
| Comparison | Statistical significance |
| Normal-vs-Primary | 8.93729534823251E-14 |
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KIRC : Kidney renal clear cell carcinoma Note
Cancer stage information is not available for 2 samples.
Show statistics |
Hide statistics |
| Comparison |
Statistical significance |
| Normal-vs-Stage1 |
2.07389660999979E-12 |
| Normal-vs-Stage2 |
1.239600E-04 |
| Normal-vs-Stage3 |
7.89210000018414E-07 |
| Normal-vs-Stage4 |
2.70370000055031E-07 |
| Stage1-vs-Stage2 |
4.423400E-01 |
| Stage1-vs-Stage3 |
1.940820E-01 |
| Stage1-vs-Stage4 |
4.691600E-01 |
| Stage2-vs-Stage3 |
8.529400E-01 |
| Stage2-vs-Stage4 |
2.748600E-01 |
| Stage3-vs-Stage4 |
1.341450E-01 |
|
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KIRC : Kidney renal clear cell carcinoma Note
Patient race information is not available for 7 samples.
Show statistics |
Hide statistics |
| Comparison |
Statistical significance |
| Normal-vs-Caucasian |
1.74538161701321E-12 |
| Normal-vs-AfricanAmerican |
5.783700E-04 |
| Normal-vs-Asian |
2.497600E-02 |
| Caucasian-vs-AfricanAmerican |
4.702800E-01 |
| Caucasian-vs-Asian |
2.852200E-01 |
| AfricanAmerican-vs-Asian |
2.299400E-01 |
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KIRC : Kidney renal clear cell carcinoma
Show statistics |
Hide statistics |
| Comparison |
Statistical significance |
| Normal-vs-Male |
6.87629952977886E-11 |
| Normal-vs-Female |
1.68032254777017E-12 |
| Male-vs-Female |
3.773600E-02 |
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KIRC : Kidney renal clear cell carcinoma
Show statistics |
Hide statistics |
| Comparison |
Statistical significance |
| Normal-vs-Age(21-40Yrs) |
3.421000E-03 |
| Normal-vs-Age(41-60Yrs) |
1.64335212105016E-12 |
| Normal-vs-Age(61-80Yrs) |
5.3712001513162E-10 |
| Normal-vs-Age(81-100Yrs) |
3.297800E-01 |
| Age(21-40Yrs)-vs-Age(41-60Yrs) |
8.373000E-01 |
| Age(21-40Yrs)-vs-Age(61-80Yrs) |
3.677800E-01 |
| Age(21-40Yrs)-vs-Age(81-100Yrs) |
2.353800E-02 |
| Age(41-60Yrs)-vs-Age(61-80Yrs) |
3.688200E-02 |
| Age(41-60Yrs)-vs-Age(81-100Yrs) |
4.565000E-04 |
| Age(61-80Yrs)-vs-Age(81-100Yrs) |
3.041800E-02 |
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KIRC : Kidney renal clear cell carcinoma Note
Tumor grade information is not available for 3 samples and undetermined for 5 samples.
| Subtype descriptions |
| Grade 1 | Well differentiated (low grade) |
Grade 2 | Moderately differentiated (intermediate grade) |
| Grade 3 | Poorly differentiated (high grade) |
Grade 4 | Undifferentiated (high grade) |
Show statistics |
Hide statistics |
| Comparison |
Statistical significance |
| Normal-vs-Grade 1 |
2.59499999266666E-09 |
| Normal-vs-Grade 2 |
1.18871579246616E-12 |
| Normal-vs-Grade 3 |
1.52989998447595E-09 |
| Normal-vs-Grade 4 |
3.59320000000718E-05 |
| Grade 1-vs-Grade 2 |
8.897600E-02 |
| Grade 1-vs-Grade 3 |
1.643670E-02 |
| Grade 1-vs-Grade 4 |
8.406200E-02 |
| Grade 2-vs-Grade 3 |
1.493410E-01 |
| Grade 2-vs-Grade 4 |
9.867000E-01 |
| Grade 3-vs-Grade 4 |
4.064400E-01 |
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KIRC : Kidney renal clear cell carcinoma NOTE
Subtype information is not available for 153 samples.
Show statistics |
Hide statistics |
| Comparison |
Statistical significance |
| Normal-vs-ccA subtype |
3.02202707302968E-13 |
| Normal-vs-ccB subtype |
2.55209964272751E-10 |
| ccA subtype-vs-ccB subtype |
6.702000E-01 |
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KIRC subtypes: Brooks SA et al, ClearCode34: A prognostic risk predictor for localized clear cell renal cell carcinoma. Eur Urol. 2014 Jul;66(1):77-84. doi: 10.1016/j.eururo.2014.02.035
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KIRC : Kidney renal clear cell carcinoma Note
Cancer in nearby lymph nodes cannot be measured (NX) in 277 samples.
| pathologic_N descriptions |
| N0 | No regional lymph node metastasis |
N1 | Metastases in 1 to 3 axillary lymph nodes |
| N2 | Metastases in 4 to 9 axillary lymph nodes |
N3 | Metastases in 10 or more axillary lymph nodes |
Show statistics |
Hide statistics |
| Comparison |
Statistical significance |
| Normal-vs-N0 |
2.82340817392424E-12 |
| Normal-vs-N1 |
5.164600E-03 |
| N0-vs-N1 |
1.291160E-01 |
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