SFRP2 promoter methylation profile based on
|
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
*
Please note that low number(<10) of normal samples considered.
Illumina Id |
RefGene_group |
cg01821854 |
TSS1500 |
cg13732865 |
TSS1500 |
cg14435644 |
TSS1500 |
cg05241277 |
TSS1500 |
cg25775322 |
TSS200 |
cg25645268 |
TSS1500 |
cg23207990 |
TSS1500 |
cg24968721 |
TSS1500 |
cg21630608 |
TSS1500 |
cg10942078 |
TSS1500 |
cg23292160 |
TSS200 |
cg14330641 |
TSS200 |
cg20881942 |
TSS1500 |
cg04959480 |
TSS1500 |
cg23714408 |
TSS1500 |
cg03202804 |
TSS200 |
cg09788843 |
TSS1500 |
cg01298731 |
TSS1500 |
cg05961809 |
TSS1500 |
cg11354906 |
TSS200 |
cg07999845 |
TSS1500 |
cg05050042 |
TSS1500 |
cg20727217 |
TSS1500 |
cg21657059 |
TSS1500 |
cg05164933 |
TSS200 |
cg24241928 |
TSS1500 |
cg23502475 |
TSS1500 |
cg00705808 |
TSS1500 |
cg13357229 |
TSS1500 |
cg10790791 |
TSS1500 |
cg23910835 |
TSS1500 |
cg00082664 |
TSS1500 |
cg14289246 |
TSS1500 |
cg22178613 |
TSS1500 |
cg10663078 |
TSS1500 |
cg04965141 |
TSS1500 |
cg23121156 |
TSS200 |
|
Comparison | Statistical significance |
Normal-vs-Primary | 2.638800E-01 |
|
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
*
Please note that low number(<10) of normal samples considered.
NOTEa
Cancer stage information is not available for 11 samples.
Illumina Id |
RefGene_group |
cg01821854 |
TSS1500 |
cg13732865 |
TSS1500 |
cg14435644 |
TSS1500 |
cg05241277 |
TSS1500 |
cg25775322 |
TSS200 |
cg25645268 |
TSS1500 |
cg23207990 |
TSS1500 |
cg24968721 |
TSS1500 |
cg21630608 |
TSS1500 |
cg10942078 |
TSS1500 |
cg23292160 |
TSS200 |
cg14330641 |
TSS200 |
cg20881942 |
TSS1500 |
cg04959480 |
TSS1500 |
cg23714408 |
TSS1500 |
cg03202804 |
TSS200 |
cg09788843 |
TSS1500 |
cg01298731 |
TSS1500 |
cg05961809 |
TSS1500 |
cg11354906 |
TSS200 |
cg07999845 |
TSS1500 |
cg05050042 |
TSS1500 |
cg20727217 |
TSS1500 |
cg21657059 |
TSS1500 |
cg05164933 |
TSS200 |
cg24241928 |
TSS1500 |
cg23502475 |
TSS1500 |
cg00705808 |
TSS1500 |
cg13357229 |
TSS1500 |
cg10790791 |
TSS1500 |
cg23910835 |
TSS1500 |
cg00082664 |
TSS1500 |
cg14289246 |
TSS1500 |
cg22178613 |
TSS1500 |
cg10663078 |
TSS1500 |
cg04965141 |
TSS1500 |
cg23121156 |
TSS200 |
|
Show statistics |
Hide statistics |
Comparison |
Statistical significance |
Normal-vs-Stage1 |
2.580600E-01 |
Normal-vs-Stage2 |
2.604400E-01 |
Normal-vs-Stage3 |
2.549400E-01 |
Normal-vs-Stage4 |
3.688000E-01 |
Stage1-vs-Stage2 |
2.262400E-01 |
Stage1-vs-Stage3 |
4.447600E-01 |
Stage1-vs-Stage4 |
1.954800E-01 |
Stage2-vs-Stage3 |
5.194800E-01 |
Stage2-vs-Stage4 |
5.305400E-01 |
Stage3-vs-Stage4 |
3.225800E-01 |
|
|
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
*
Please note that low number(<10) of normal samples considered.
NOTEa
Patient race information is not available for 39 samples. One sample from Native Hawaiian are not considered in the above plot
Illumina Id |
RefGene_group |
cg01821854 |
TSS1500 |
cg13732865 |
TSS1500 |
cg14435644 |
TSS1500 |
cg05241277 |
TSS1500 |
cg25775322 |
TSS200 |
cg25645268 |
TSS1500 |
cg23207990 |
TSS1500 |
cg24968721 |
TSS1500 |
cg21630608 |
TSS1500 |
cg10942078 |
TSS1500 |
cg23292160 |
TSS200 |
cg14330641 |
TSS200 |
cg20881942 |
TSS1500 |
cg04959480 |
TSS1500 |
cg23714408 |
TSS1500 |
cg03202804 |
TSS200 |
cg09788843 |
TSS1500 |
cg01298731 |
TSS1500 |
cg05961809 |
TSS1500 |
cg11354906 |
TSS200 |
cg07999845 |
TSS1500 |
cg05050042 |
TSS1500 |
cg20727217 |
TSS1500 |
cg21657059 |
TSS1500 |
cg05164933 |
TSS200 |
cg24241928 |
TSS1500 |
cg23502475 |
TSS1500 |
cg00705808 |
TSS1500 |
cg13357229 |
TSS1500 |
cg10790791 |
TSS1500 |
cg23910835 |
TSS1500 |
cg00082664 |
TSS1500 |
cg14289246 |
TSS1500 |
cg22178613 |
TSS1500 |
cg10663078 |
TSS1500 |
cg04965141 |
TSS1500 |
cg23121156 |
TSS200 |
|
Show statistics |
Hide statistics |
Comparison |
Statistical significance |
Normal-vs-Caucasian |
2.840600E-01 |
Normal-vs-AfricanAmerican |
2.649800E-01 |
Normal-vs-Asian |
1.968970E-01 |
Caucasian-vs-AfricanAmerican |
4.947200E-01 |
Caucasian-vs-Asian |
4.677500E-02 |
AfricanAmerican-vs-Asian |
8.623600E-01 |
|
|
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
*
Please note that low number(<10) of normal samples considered.
Illumina Id |
RefGene_group |
cg01821854 |
TSS1500 |
cg13732865 |
TSS1500 |
cg14435644 |
TSS1500 |
cg05241277 |
TSS1500 |
cg25775322 |
TSS200 |
cg25645268 |
TSS1500 |
cg23207990 |
TSS1500 |
cg24968721 |
TSS1500 |
cg21630608 |
TSS1500 |
cg10942078 |
TSS1500 |
cg23292160 |
TSS200 |
cg14330641 |
TSS200 |
cg20881942 |
TSS1500 |
cg04959480 |
TSS1500 |
cg23714408 |
TSS1500 |
cg03202804 |
TSS200 |
cg09788843 |
TSS1500 |
cg01298731 |
TSS1500 |
cg05961809 |
TSS1500 |
cg11354906 |
TSS200 |
cg07999845 |
TSS1500 |
cg05050042 |
TSS1500 |
cg20727217 |
TSS1500 |
cg21657059 |
TSS1500 |
cg05164933 |
TSS200 |
cg24241928 |
TSS1500 |
cg23502475 |
TSS1500 |
cg00705808 |
TSS1500 |
cg13357229 |
TSS1500 |
cg10790791 |
TSS1500 |
cg23910835 |
TSS1500 |
cg00082664 |
TSS1500 |
cg14289246 |
TSS1500 |
cg22178613 |
TSS1500 |
cg10663078 |
TSS1500 |
cg04965141 |
TSS1500 |
cg23121156 |
TSS200 |
|
Show statistics |
Hide statistics |
Comparison |
Statistical significance |
Normal-vs-Male |
2.603000E-01 |
Normal-vs-Female |
2.765400E-01 |
Male-vs-Female |
8.147200E-01 |
|
|
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
*
Please note that low number(<10) of normal samples considered.
NOTEa
Patient age information is not available for 5 samples.
Illumina Id |
RefGene_group |
cg01821854 |
TSS1500 |
cg13732865 |
TSS1500 |
cg14435644 |
TSS1500 |
cg05241277 |
TSS1500 |
cg25775322 |
TSS200 |
cg25645268 |
TSS1500 |
cg23207990 |
TSS1500 |
cg24968721 |
TSS1500 |
cg21630608 |
TSS1500 |
cg10942078 |
TSS1500 |
cg23292160 |
TSS200 |
cg14330641 |
TSS200 |
cg20881942 |
TSS1500 |
cg04959480 |
TSS1500 |
cg23714408 |
TSS1500 |
cg03202804 |
TSS200 |
cg09788843 |
TSS1500 |
cg01298731 |
TSS1500 |
cg05961809 |
TSS1500 |
cg11354906 |
TSS200 |
cg07999845 |
TSS1500 |
cg05050042 |
TSS1500 |
cg20727217 |
TSS1500 |
cg21657059 |
TSS1500 |
cg05164933 |
TSS200 |
cg24241928 |
TSS1500 |
cg23502475 |
TSS1500 |
cg00705808 |
TSS1500 |
cg13357229 |
TSS1500 |
cg10790791 |
TSS1500 |
cg23910835 |
TSS1500 |
cg00082664 |
TSS1500 |
cg14289246 |
TSS1500 |
cg22178613 |
TSS1500 |
cg10663078 |
TSS1500 |
cg04965141 |
TSS1500 |
cg23121156 |
TSS200 |
|
Show statistics |
Hide statistics |
Comparison |
Statistical significance |
Normal-vs-Age(21-40Yrs) |
1.293750E-01 |
Normal-vs-Age(41-60Yrs) |
3.073800E-01 |
Normal-vs-Age(61-80Yrs) |
2.538800E-01 |
Normal-vs-Age(81-100Yrs) |
1.612200E-01 |
Age(21-40Yrs)-vs-Age(41-60Yrs) |
1.512980E-01 |
Age(21-40Yrs)-vs-Age(61-80Yrs) |
3.416800E-01 |
Age(21-40Yrs)-vs-Age(81-100Yrs) |
2.460600E-01 |
Age(41-60Yrs)-vs-Age(61-80Yrs) |
1.135830E-01 |
Age(41-60Yrs)-vs-Age(81-100Yrs) |
4.531600E-01 |
Age(61-80Yrs)-vs-Age(81-100Yrs) |
9.373400E-01 |
|
|
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
*
Please note that low number(<10) of normal samples considered.
NOTEa
Grade cannot be assessed(GX) for 9 samples.
Illumina Id |
RefGene_group |
cg01821854 |
TSS1500 |
cg13732865 |
TSS1500 |
cg14435644 |
TSS1500 |
cg05241277 |
TSS1500 |
cg25775322 |
TSS200 |
cg25645268 |
TSS1500 |
cg23207990 |
TSS1500 |
cg24968721 |
TSS1500 |
cg21630608 |
TSS1500 |
cg10942078 |
TSS1500 |
cg23292160 |
TSS200 |
cg14330641 |
TSS200 |
cg20881942 |
TSS1500 |
cg04959480 |
TSS1500 |
cg23714408 |
TSS1500 |
cg03202804 |
TSS200 |
cg09788843 |
TSS1500 |
cg01298731 |
TSS1500 |
cg05961809 |
TSS1500 |
cg11354906 |
TSS200 |
cg07999845 |
TSS1500 |
cg05050042 |
TSS1500 |
cg20727217 |
TSS1500 |
cg21657059 |
TSS1500 |
cg05164933 |
TSS200 |
cg24241928 |
TSS1500 |
cg23502475 |
TSS1500 |
cg00705808 |
TSS1500 |
cg13357229 |
TSS1500 |
cg10790791 |
TSS1500 |
cg23910835 |
TSS1500 |
cg00082664 |
TSS1500 |
cg14289246 |
TSS1500 |
cg22178613 |
TSS1500 |
cg10663078 |
TSS1500 |
cg04965141 |
TSS1500 |
cg23121156 |
TSS200 |
|
Show statistics |
Hide statistics |
Comparison |
Statistical significance |
Normal-vs-Grade1 |
4.193600E-01 |
Normal-vs-Grade2 |
2.377000E-01 |
Normal-vs-Grade3 |
2.755400E-01 |
Grade1-vs-Grade2 |
6.498600E-01 |
Grade1-vs-Grade3 |
9.534400E-01 |
Grade2-vs-Grade3 |
8.537900E-02 |
|
|
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
*
Please note that low number(<10) of normal samples considered.
Illumina Id |
RefGene_group |
cg01821854 |
TSS1500 |
cg13732865 |
TSS1500 |
cg14435644 |
TSS1500 |
cg05241277 |
TSS1500 |
cg25775322 |
TSS200 |
cg25645268 |
TSS1500 |
cg23207990 |
TSS1500 |
cg24968721 |
TSS1500 |
cg21630608 |
TSS1500 |
cg10942078 |
TSS1500 |
cg23292160 |
TSS200 |
cg14330641 |
TSS200 |
cg20881942 |
TSS1500 |
cg04959480 |
TSS1500 |
cg23714408 |
TSS1500 |
cg03202804 |
TSS200 |
cg09788843 |
TSS1500 |
cg01298731 |
TSS1500 |
cg05961809 |
TSS1500 |
cg11354906 |
TSS200 |
cg07999845 |
TSS1500 |
cg05050042 |
TSS1500 |
cg20727217 |
TSS1500 |
cg21657059 |
TSS1500 |
cg05164933 |
TSS200 |
cg24241928 |
TSS1500 |
cg23502475 |
TSS1500 |
cg00705808 |
TSS1500 |
cg13357229 |
TSS1500 |
cg10790791 |
TSS1500 |
cg23910835 |
TSS1500 |
cg00082664 |
TSS1500 |
cg14289246 |
TSS1500 |
cg22178613 |
TSS1500 |
cg10663078 |
TSS1500 |
cg04965141 |
TSS1500 |
cg23121156 |
TSS200 |
|
Show statistics |
Hide statistics |
Comparison |
Statistical significance |
Normal-vs-N0 |
2.380000E-01 |
Normal-vs-N1 |
2.846800E-01 |
Normal-vs-N2 |
2.472000E-01 |
Normal-vs-N3 |
3.165400E-01 |
N0-vs-N1 |
9.614000E-01 |
N0-vs-N2 |
7.367200E-01 |
N0-vs-N3 |
2.885200E-01 |
N1-vs-N2 |
7.284000E-01 |
N1-vs-N3 |
3.564000E-01 |
N2-vs-N3 |
2.170600E-01 |
|
|
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data.
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
*
Please note that low number(<10) of normal samples considered.
Illumina Id |
RefGene_group |
cg01821854 |
TSS1500 |
cg13732865 |
TSS1500 |
cg14435644 |
TSS1500 |
cg05241277 |
TSS1500 |
cg25775322 |
TSS200 |
cg25645268 |
TSS1500 |
cg23207990 |
TSS1500 |
cg24968721 |
TSS1500 |
cg21630608 |
TSS1500 |
cg10942078 |
TSS1500 |
cg23292160 |
TSS200 |
cg14330641 |
TSS200 |
cg20881942 |
TSS1500 |
cg04959480 |
TSS1500 |
cg23714408 |
TSS1500 |
cg03202804 |
TSS200 |
cg09788843 |
TSS1500 |
cg01298731 |
TSS1500 |
cg05961809 |
TSS1500 |
cg11354906 |
TSS200 |
cg07999845 |
TSS1500 |
cg05050042 |
TSS1500 |
cg20727217 |
TSS1500 |
cg21657059 |
TSS1500 |
cg05164933 |
TSS200 |
cg24241928 |
TSS1500 |
cg23502475 |
TSS1500 |
cg00705808 |
TSS1500 |
cg13357229 |
TSS1500 |
cg10790791 |
TSS1500 |
cg23910835 |
TSS1500 |
cg00082664 |
TSS1500 |
cg14289246 |
TSS1500 |
cg22178613 |
TSS1500 |
cg10663078 |
TSS1500 |
cg04965141 |
TSS1500 |
cg23121156 |
TSS200 |
|
Show statistics |
Hide statistics |
Comparison |
Statistical significance |
Normal-vs-TP53 Mutant |
2.740800E-01 |
Normal-vs-TP53 NonMutant |
2.587000E-01 |
TP53 Mutant-vs-TP53 NonMutant |
7.466200E-01 |
|
|