SFRP1 promoter methylation profile based on  


The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739



PROBES CLICK TO SEE PROBE LIST.
Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
   
*  Please note that low number(<10) of normal samples considered.




Comparison Statistical significance
Normal-vs-Primary 8.743800E-01
Normal-vs-Metastasis 7.223700E-03
Primary-vs-Metastasis 7.932800E-01