Welcome to UALCAN analysis page.

Yes! You All Can

The University of ALabama at Birmingham CANcer data analysis Portal

UALCAN provides protein expression analysis option using data from Clinical Proteomic Tumor Analysis Consortium (CPTAC) and the International Cancer Proteogenome Consortium (ICPC) datasets. The protein expression for Colorectal cancer, Breast cancer, Ovarian cancer, Clear cell renal cell carcinoma, Uterine corpus endometrial carcinoma, Gastric cancer, Glioblastoma, Pediatric brain tumors, Head and Neck squamous cell carcinoma, Lung adenocarcinoma, Lung squamous cell carcinoma, Liver cancer, Pancreatic cancer, and Prostate cancer is available.

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CPTAC dataset

   
   
 

References:   Chen F, Zhang Y, Chandrashekar DS, Varambally S, Creighton CJ. Global impact of somatic structural variation on the cancer proteome. Nature Communications, 2023 Sept., 13 ;14(1):5637. doi: 10.1038/s41467-023-41374-8  

 Zhang, Y., Chen, F., Chandrashekar, D.S., Varambally, S., Creighton, C.J. Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways. Nat Commun 13, 2669 (2022) doi: 10.1038/s41467-022-30342-3

Chen, F., Chandrashekar, D.S., Varambally, S., Creighton, C.J. Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers. Nat Commun 10, 5679 (2019) doi:10.1038/s41467-019-13528-0

 Chandrashekar DS, Karthikeyan SK, Korla PK, Patel H, Shovon AR, Athar M, Netto GJ, Qin ZS, Kumar S, Manne U, Creighton CJ, Varambally S. UALCAN: An update to the integrated cancer data analysis platform. Neoplasia. 2022 Mar;25:18-27. doi: 10.1016/j.neo.2022.01.001