GLS expression based on
PRAD : Prostate adenocarcinoma
Comparison Statistical significance Normal-vs-Primary 3.586100E-02
Pan-cancer view
Methylation
Survival
ChIP-seq data
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma
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Comparison Statistical significance
Normal-vs-Caucasian
9.624400E-01
Normal-vs-AfricanAmerican
7.113000E-01
Caucasian-vs-AfricanAmerican
7.675800E-01
Pan-cancer view
Methylation
Survival
ChIP-seq data
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma
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Comparison Statistical significance
Normal-vs-Age(41-60Yrs)
N/A
Normal-vs-Age(61-80Yrs)
N/A
Age(41-60Yrs)-vs-Age(61-80Yrs)
4.026400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma Note
Gleason score information is not available for 1 sample.
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Comparison Statistical significance
Normal-vs-Gleason score 6
3.181000E-04
Normal-vs-Gleason score 7
1.582710E-03
Normal-vs-Gleason score 8
3.873200E-01
Normal-vs-Gleason score 9
7.699400E-01
Normal-vs-Gleason score 10
2.189000E-01
Gleason score 6-vs-Gleason score 7
2.560600E-01
Gleason score 6-vs-Gleason score 8
1.531750E-02
Gleason score 6-vs-Gleason score 9
1.753800E-04
Gleason score 6-vs-Gleason score 10
1.257370E-01
Gleason score 7-vs-Gleason score 8
3.359500E-02
Gleason score 7-vs-Gleason score 9
3.61859999999936E-05
Gleason score 7-vs-Gleason score 10
1.413580E-01
Gleason score 8-vs-Gleason score 9
4.627400E-01
Gleason score 8-vs-Gleason score 10
1.886390E-01
Gleason score 9-vs-Gleason score 10
2.090200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma PRAD molecular subtypes: Cancer Genome Atlas Research Network, The Molecular Taxonomy of Primary Prostate Cancer. Cell. 2015;163(4):1011-25
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Comparison Statistical significance
Normal-vs-ERG fusion
8.944200E-01
Normal-vs-ETV1 fusion
4.716200E-01
Normal-vs-ETV4 fusion
1.120250E-01
Normal-vs-FLI1 fusion
1.471770E-02
Normal-vs-FOXA1 mutation
9.415000E-01
Normal-vs-IDH1 mutation
7.318400E-01
Normal-vs-SPOP mutation
6.734100E-02
ERG fusion-vs-ETV1 fusion
4.805000E-01
ERG fusion-vs-ETV4 fusion
9.338200E-02
ERG fusion-vs-FLI1 fusion
1.460170E-02
ERG fusion-vs-FOXA1 mutation
8.915200E-01
ERG fusion-vs-IDH1 mutation
7.077200E-01
ERG fusion-vs-SPOP mutation
2.978400E-02
ETV1 fusion-vs-ETV4 fusion
3.748600E-01
ETV1 fusion-vs-FLI1 fusion
5.642100E-02
ETV1 fusion-vs-FOXA1 mutation
5.976000E-01
ETV1 fusion-vs-IDH1 mutation
5.560800E-01
ETV1 fusion-vs-SPOP mutation
2.860400E-02
ETV4 fusion-vs-FLI1 fusion
2.887800E-01
ETV4 fusion-vs-FOXA1 mutation
2.676400E-01
ETV4 fusion-vs-IDH1 mutation
3.832000E-01
ETV4 fusion-vs-SPOP mutation
8.175100E-03
FLI1 fusion-vs-FOXA1 mutation
2.215600E-02
FLI1 fusion-vs-IDH1 mutation
1.124010E-01
FLI1 fusion-vs-SPOP mutation
1.461560E-03
FOXA1 mutation-vs-IDH1 mutation
7.314000E-01
FOXA1 mutation-vs-SPOP mutation
2.735400E-01
IDH1 mutation-vs-SPOP mutation
7.337800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma Note
Nodal metastais status is not available for 73 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison Statistical significance
Normal-vs-N0
2.193900E-02
Normal-vs-N1
8.249200E-01
N0-vs-N1
1.851680E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma Note
Whole exome sequencing data is not available for 164 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison Statistical significance
Normal-vs-TP53-Mutant
7.532600E-01
Normal-vs-TP53-NonMutant
2.156300E-02
TP53-Mutant-vs-TP53-NonMutant
5.996100E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
GLS expression based on
PRAD : Prostate adenocarcinoma
Comparison Statistical significance Normal-vs-Primary 3.586100E-02
Pan-cancer view
Methylation
Survival
ChIP-seq data
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Caucasian
9.624400E-01
Normal-vs-AfricanAmerican
7.113000E-01
Caucasian-vs-AfricanAmerican
7.675800E-01
Pan-cancer view
Methylation
Survival
ChIP-seq data
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-Age(41-60Yrs)
N/A
Normal-vs-Age(61-80Yrs)
N/A
Age(41-60Yrs)-vs-Age(61-80Yrs)
4.026400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma Note
Gleason score information is not available for 1 sample.
Show statistics
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Comparison Statistical significance
Normal-vs-Gleason score 6
3.181000E-04
Normal-vs-Gleason score 7
1.582710E-03
Normal-vs-Gleason score 8
3.873200E-01
Normal-vs-Gleason score 9
7.699400E-01
Normal-vs-Gleason score 10
2.189000E-01
Gleason score 6-vs-Gleason score 7
2.560600E-01
Gleason score 6-vs-Gleason score 8
1.531750E-02
Gleason score 6-vs-Gleason score 9
1.753800E-04
Gleason score 6-vs-Gleason score 10
1.257370E-01
Gleason score 7-vs-Gleason score 8
3.359500E-02
Gleason score 7-vs-Gleason score 9
3.61859999999936E-05
Gleason score 7-vs-Gleason score 10
1.413580E-01
Gleason score 8-vs-Gleason score 9
4.627400E-01
Gleason score 8-vs-Gleason score 10
1.886390E-01
Gleason score 9-vs-Gleason score 10
2.090200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma PRAD molecular subtypes: Cancer Genome Atlas Research Network, The Molecular Taxonomy of Primary Prostate Cancer. Cell. 2015;163(4):1011-25
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-ERG fusion
8.944200E-01
Normal-vs-ETV1 fusion
4.716200E-01
Normal-vs-ETV4 fusion
1.120250E-01
Normal-vs-FLI1 fusion
1.471770E-02
Normal-vs-FOXA1 mutation
9.415000E-01
Normal-vs-IDH1 mutation
7.318400E-01
Normal-vs-SPOP mutation
6.734100E-02
ERG fusion-vs-ETV1 fusion
4.805000E-01
ERG fusion-vs-ETV4 fusion
9.338200E-02
ERG fusion-vs-FLI1 fusion
1.460170E-02
ERG fusion-vs-FOXA1 mutation
8.915200E-01
ERG fusion-vs-IDH1 mutation
7.077200E-01
ERG fusion-vs-SPOP mutation
2.978400E-02
ETV1 fusion-vs-ETV4 fusion
3.748600E-01
ETV1 fusion-vs-FLI1 fusion
5.642100E-02
ETV1 fusion-vs-FOXA1 mutation
5.976000E-01
ETV1 fusion-vs-IDH1 mutation
5.560800E-01
ETV1 fusion-vs-SPOP mutation
2.860400E-02
ETV4 fusion-vs-FLI1 fusion
2.887800E-01
ETV4 fusion-vs-FOXA1 mutation
2.676400E-01
ETV4 fusion-vs-IDH1 mutation
3.832000E-01
ETV4 fusion-vs-SPOP mutation
8.175100E-03
FLI1 fusion-vs-FOXA1 mutation
2.215600E-02
FLI1 fusion-vs-IDH1 mutation
1.124010E-01
FLI1 fusion-vs-SPOP mutation
1.461560E-03
FOXA1 mutation-vs-IDH1 mutation
7.314000E-01
FOXA1 mutation-vs-SPOP mutation
2.735400E-01
IDH1 mutation-vs-SPOP mutation
7.337800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma Note
Nodal metastais status is not available for 73 samples.
pathologic_N descriptions N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
Show statistics
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Comparison Statistical significance
Normal-vs-N0
2.193900E-02
Normal-vs-N1
8.249200E-01
N0-vs-N1
1.851680E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
PRAD : Prostate adenocarcinoma Note
Whole exome sequencing data is not available for 164 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
Show statistics
Hide statistics
Comparison Statistical significance
Normal-vs-TP53-Mutant
7.532600E-01
Normal-vs-TP53-NonMutant
2.156300E-02
TP53-Mutant-vs-TP53-NonMutant
5.996100E-02
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
