The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Comparison
Statistical significance
Normal-vs-Primary
1.00479957687583E-10
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
NOTEa
Cancer stage information is not available for 2 samples.
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Show statistics
Hide statistics
Comparison
Statistical significance
Normal-vs-Stage1
1.760650E-01
Normal-vs-Stage2
5.662800228734E-10
Normal-vs-Stage3
2.47240000028626E-07
Normal-vs-Stage4
1.30995214675522E-12
Stage1-vs-Stage2
6.613800E-01
Stage1-vs-Stage3
4.164400E-01
Stage1-vs-Stage4
8.408200E-01
Stage2-vs-Stage3
1.272360E-01
Stage2-vs-Stage4
2.714600E-01
Stage3-vs-Stage4
6.364600E-03
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
NOTEa
Patient race information is not available for 18 samples.
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Show statistics
Hide statistics
Comparison
Statistical significance
Normal-vs-Caucasian
1.19919962848769E-10
Normal-vs-AfricanAmerican
6.987400E-04
Normal-vs-Asian
5.768800E-04
Caucasian-vs-AfricanAmerican
9.030800E-01
Caucasian-vs-Asian
4.340200E-01
AfricanAmerican-vs-Asian
5.858600E-01
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Show statistics
Hide statistics
Comparison
Statistical significance
Normal-vs-Male
5.87060400292216E-11
Normal-vs-Female
4.15000001030563E-09
Male-vs-Female
7.794000E-01
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Show statistics
Hide statistics
Comparison
Statistical significance
Normal-vs-Age(21-40Yrs)
4.891400E-01
Normal-vs-Age(41-60Yrs)
4.13860001824418E-09
Normal-vs-Age(61-80Yrs)
3.36550010082703E-10
Normal-vs-Age(81-100Yrs)
7.70510000247526E-09
Age(21-40Yrs)-vs-Age(41-60Yrs)
8.879000E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
7.806600E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
9.531000E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
5.031200E-01
Age(41-60Yrs)-vs-Age(81-100Yrs)
6.302400E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
2.958400E-01
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
NOTEa
Height/Weight information is not available for 50 samples, while 9 samples from patients with BMI < 18.5 are not considered in above plot.
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Show statistics
Hide statistics
Comparison
Statistical significance
Normal-vs-NormalWeight
1.06569999491768E-08
Normal-vs-ExtremeWeight
3.93849997060158E-09
Normal-vs-Obese
1.90570004221513E-09
Normal-vs-ExtremeObese
2.901000E-03
NormalWeight-vs-ExtremeWeight
5.183200E-01
NormalWeight-vs-Obese
1.788780E-01
NormalWeight-vs-ExtremeObese
2.938200E-01
ExtremeWeight-vs-Obese
4.890200E-01
ExtremeWeight-vs-ExtremeObese
4.920200E-01
Obese-vs-ExtremeObese
7.105600E-01
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Show statistics
Hide statistics
Comparison
Statistical significance
Normal-vs-NonSmoker
1.53449997153388E-09
Normal-vs-Smoker
4.81580000000204E-06
Normal-vs-ReformedSmoker1
4.29330004880768E-09
Normal-vs-ReformedSmoker2
1.23669963159045E-10
NonSmoker-vs-Smoker
2.305000E-01
NonSmoker-vs-ReformedSmoker1
3.886000E-01
NonSmoker-vs-ReformedSmoker2
5.187800E-01
Smoker-vs-ReformedSmoker1
7.390000E-02
Smoker-vs-ReformedSmoker2
8.012400E-02
ReformedSmoker1-vs-ReformedSmoker2
7.714000E-01
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Show statistics
Hide statistics
Comparison
Statistical significance
Normal-vs-N0
1.75769998556063E-09
Normal-vs-N1
1.85209999559177E-08
Normal-vs-N2
8.34590174747518E-11
Normal-vs-N3
7.078100E-02
N0-vs-N1
3.858100E-02
N0-vs-N2
8.569800E-02
N0-vs-N3
8.766800E-01
N1-vs-N2
5.177800E-01
N1-vs-N3
4.797400E-01
N2-vs-N3
6.289400E-01
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
Illumina Id
RefGene_group
cg01821854
TSS1500
cg13732865
TSS1500
cg14435644
TSS1500
cg05241277
TSS1500
cg25775322
TSS200
cg25645268
TSS1500
cg23207990
TSS1500
cg24968721
TSS1500
cg21630608
TSS1500
cg10942078
TSS1500
cg23292160
TSS200
cg14330641
TSS200
cg20881942
TSS1500
cg04959480
TSS1500
cg23714408
TSS1500
cg03202804
TSS200
cg09788843
TSS1500
cg01298731
TSS1500
cg05961809
TSS1500
cg11354906
TSS200
cg07999845
TSS1500
cg05050042
TSS1500
cg20727217
TSS1500
cg21657059
TSS1500
cg05164933
TSS200
cg24241928
TSS1500
cg23502475
TSS1500
cg00705808
TSS1500
cg13357229
TSS1500
cg10790791
TSS1500
cg23910835
TSS1500
cg00082664
TSS1500
cg14289246
TSS1500
cg22178613
TSS1500
cg10663078
TSS1500
cg04965141
TSS1500
cg23121156
TSS200
Show statistics
Hide statistics
Comparison
Statistical significance
Normal-vs-Papillary tumor
2.79040124340213E-11
Normal-vs-Non papillary tumor
4.02090027940005E-10
Papillary tumor-vs-Non papillary tumor
2.002600E-01
The Beta value indicates level of DNA methylation ranging from 0 (unmethylated) to 1 (fully methylated). Different beta value cut-off has been considered to indicate hyper-methylation [Beta value: 0.7 - 0.5] or hypo-methylation [Beta-value: 0.3 - 0.25]. PMID: 29027401, 23291739
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data.
PROBES
CLICK TO SEE PROBE LIST. Please note that the Beta value is the ratio of the methylated probe intensity and the sum of methylated and unmethylated probe intensity. Beta value ranges from 0 to 1. The above boxplot represents beta values of CpG probes located upto 1500bp upstream of gene's start site [TSS200, TSS1500]
NOTEa
Whole exome sequencing data is not available for 13 samples.