CYP2C8 expression profile based on
SKCM : Skin cutaneous melanoma *
Please note that the TPM values for gene considered is extremely low (TPM < 1).
*
Please note that low number(<10) of normal samples considered.
Comparison
Statistical significance
Normal-vs-Primary
N/A
Normal-vs-Metastasis
N/A
Primary-vs-Metastasis
4.245200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
SKCM : Skin cutaneous melanoma *
Please note that the TPM values for gene considered is extremely low (TPM < 1).
*
Please note that low number(<10) of normal samples considered.
Note
Cancer stage information is not available for 57 samples. Six samples marked as "Stage 0" are not represented in the above plot.
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Comparison
Statistical significance
Normal-vs-Stage1
N/A
Normal-vs-Stage2
N/A
Normal-vs-Stage3
N/A
Normal-vs-Stage4
N/A
Stage1-vs-Stage2
3.654800E-01
Stage1-vs-Stage3
6.651000E-01
Stage1-vs-Stage4
4.911000E-01
Stage2-vs-Stage3
4.583400E-01
Stage2-vs-Stage4
2.424400E-01
Stage3-vs-Stage4
2.902200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
SKCM : Skin cutaneous melanoma *
Please note that the TPM values for gene considered is extremely low (TPM < 1).
*
Please note that low number(<10) of normal samples considered.
Note
Patient race information is not available for 21 samples.
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Comparison
Statistical significance
Normal-vs-Caucasian
N/A
Normal-vs-AfricanAmerican
N/A
Normal-vs-Asian
N/A
Caucasian-vs-AfricanAmerican
N/A
Caucasian-vs-Asian
7.256400E-01
AfricanAmerican-vs-Asian
N/A
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
SKCM : Skin cutaneous melanoma *
Please note that the TPM values for gene considered is extremely low (TPM < 1).
*
Please note that low number(<10) of normal samples considered.
Note
Patient gender information is not available for 11 samples.
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Comparison
Statistical significance
Normal-vs-Male
N/A
Normal-vs-Female
N/A
Male-vs-Female
2.750800E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
SKCM : Skin cutaneous melanoma *
Please note that the TPM values for gene considered is extremely low (TPM < 1).
*
Please note that low number(<10) of normal samples considered.
Note
Patient BMI information is not available for 231 samples.
Descriptions
Normal weight
BMI greater than equal to 18.5 and BMI less than 25
Extereme weight
BMI greater than equal to 25 and BMI less than 30
Obese
BMI greater than equal to 30 and BMI less than 40
Extreme Obese
BMI greater than 40
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Comparison
Statistical significance
Normal-vs-Normal_Weight
N/A
Normal-vs-Extreme_Weight
N/A
Normal-vs-Obese
N/A
Normal-vs-Extreme_Obese
N/A
Normal_Weight-vs-Extreme_Weight
6.188400E-01
Normal_Weight-vs-Obese
9.377200E-01
Normal_Weight-vs-Extreme_Obese
7.634200E-01
Extreme_Weight-vs-Obese
6.551400E-01
Extreme_Weight-vs-Extreme_Obese
5.318200E-01
Obese-vs-Extreme_Obese
7.363200E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
SKCM : Skin cutaneous melanoma *
Please note that the TPM values for gene considered is extremely low (TPM < 1).
*
Please note that low number(<10) of normal samples considered.
Note
Patient age information is not available for 11 samples. Six samples from patients below 21 years are not considered in above plot.
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Comparison
Statistical significance
Normal-vs-Age(21-40Yrs)
N/A
Normal-vs-Age(41-60Yrs)
N/A
Normal-vs-Age(61-80Yrs)
N/A
Normal-vs-Age(81-100Yrs)
N/A
Age(21-40Yrs)-vs-Age(41-60Yrs)
1.735440E-01
Age(21-40Yrs)-vs-Age(61-80Yrs)
4.662800E-01
Age(21-40Yrs)-vs-Age(81-100Yrs)
4.131800E-01
Age(41-60Yrs)-vs-Age(61-80Yrs)
2.930000E-01
Age(41-60Yrs)-vs-Age(81-100Yrs)
6.999200E-01
Age(61-80Yrs)-vs-Age(81-100Yrs)
5.282400E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
SKCM : Skin cutaneous melanoma *
Please note that the TPM values for gene considered is extremely low (TPM < 1).
*
Please note that low number(<10) of normal samples considered.
Note
Nodal metastais status is not available for 22 samples and cancer in nearby lymph nodes cannot be measured (NX) in 36 samples.
pathologic_N descriptions
N0 No regional lymph node metastasis
N1 Metastases in 1 to 3 axillary lymph nodes
N2 Metastases in 4 to 9 axillary lymph nodes
N3 Metastases in 10 or more axillary lymph nodes
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Comparison
Statistical significance
Normal-vs-N0
N/A
Normal-vs-N1
N/A
Normal-vs-N2
N/A
Normal-vs-N3
N/A
N0-vs-N1
1.672450E-01
N0-vs-N2
4.306400E-01
N0-vs-N3
9.730400E-01
N1-vs-N2
4.813200E-01
N1-vs-N3
2.677000E-01
N2-vs-N3
5.204000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap
SKCM : Skin cutaneous melanoma *
Please note that the TPM values for gene considered is extremely low (TPM < 1).
*
Please note that low number(<10) of normal samples considered.
Note
Whole exome sequencing data is not available for 11 samples.
TP53 mutation status is obtained from TCGA whole exome sequencing data. We downloaded Mutation Annotation Format (MAF) files (derived from VarScan2) from Genomic Data Commons portal. The sample with/without TP53 mutation were matched with RNA-seq data
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Comparison
Statistical significance
Normal-vs-TP53-Mutant
N/A
Normal-vs-TP53-NonMutant
N/A
TP53-Mutant-vs-TP53-NonMutant
2.574000E-01
Pan-cancer view
Methylation
Survival
Correlated genes
DepMap